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Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase

We used high-throughput sequencing of short, cyclobutane pyrimidine dimer-containing ssDNA oligos generated during repair of UV-induced damage to study that process at both mechanistic and systemic levels in Escherichia coli. Numerous important insights on DNA repair were obtained, bringing clarity...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Adebali, Ogun, Chiou, Yi-Ying, Hu, Jinchuan, Sancar, Aziz, Selby, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358382/
https://ncbi.nlm.nih.gov/pubmed/28167766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700230114
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