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Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but may be a key technology to understand the biology of myelin diseases and to develop treatments for such disorders. Here, we demonstrate that the induction of th...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Ehrlich, Marc, Mozafari, Sabah, Glatza, Michael, Starost, Laura, Velychko, Sergiy, Hallmann, Anna-Lena, Cui, Qiao-Ling, Schambach, Axel, Kim, Kee-Pyo, Bachelin, Corinne, Marteyn, Antoine, Hargus, Gunnar, Johnson, Radia Marie, Antel, Jack, Sterneckert, Jared, Zaehres, Holm, Schöler, Hans R., Baron-Van Evercooren, Anne, Kuhlmann, Tanja
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358375/
https://ncbi.nlm.nih.gov/pubmed/28246330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614412114
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