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Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity

Riboswitches are RNAs that form complex, folded structures that selectively bind small molecules or ions. As with certain groups of protein enzymes and receptors, some riboswitch classes have evolved to change their ligand specificity. We developed a procedure to systematically analyze known riboswi...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Weinberg, Zasha, Nelson, James W., Lünse, Christina E., Sherlock, Madeline E., Breaker, Ronald R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358364/
https://ncbi.nlm.nih.gov/pubmed/28265071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619581114
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