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Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity

Riboswitches are RNAs that form complex, folded structures that selectively bind small molecules or ions. As with certain groups of protein enzymes and receptors, some riboswitch classes have evolved to change their ligand specificity. We developed a procedure to systematically analyze known riboswi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Weinberg, Zasha, Nelson, James W., Lünse, Christina E., Sherlock, Madeline E., Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358364/
https://ncbi.nlm.nih.gov/pubmed/28265071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619581114
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