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Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity

Riboswitches are RNAs that form complex, folded structures that selectively bind small molecules or ions. As with certain groups of protein enzymes and receptors, some riboswitch classes have evolved to change their ligand specificity. We developed a procedure to systematically analyze known riboswi...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Weinberg, Zasha, Nelson, James W., Lünse, Christina E., Sherlock, Madeline E., Breaker, Ronald R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358364/
https://ncbi.nlm.nih.gov/pubmed/28265071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619581114
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