Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity

Riboswitches are RNAs that form complex, folded structures that selectively bind small molecules or ions. As with certain groups of protein enzymes and receptors, some riboswitch classes have evolved to change their ligand specificity. We developed a procedure to systematically analyze known riboswi...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Weinberg, Zasha, Nelson, James W., Lünse, Christina E., Sherlock, Madeline E., Breaker, Ronald R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358364/
https://ncbi.nlm.nih.gov/pubmed/28265071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619581114
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