In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development

The intestine plays a central role in digestion, nutrient absorption and metabolism, with individual regions of the intestine having distinct functional roles. Many examples of region-specific gene expression in the adult intestine are known, but how intestinal regional identity is established durin...

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Detalles Bibliográficos
Publicado en:Development
Autores principales: Tsai, Yu-Hwai, Nattiv, Roy, Dedhia, Priya H., Nagy, Melinda S., Chin, Alana M., Thomson, Matthew, Klein, Ophir D., Spence, Jason R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2017
Materias:
Human Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358103/
https://ncbi.nlm.nih.gov/pubmed/27927684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138453
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