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Engineering a lipase B from Candida antactica with efficient perhydrolysis performance by eliminating its hydrolase activity
A Ser105Ala mutant of the lipase B from Candida antarctica enables ‘perhydrolase-only’ reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially elimi...
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| Gepubliceerd in: | Sci Rep |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357956/ https://ncbi.nlm.nih.gov/pubmed/28317884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44599 |
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