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BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action

Polybrominated diphenyl ethers (PBDEs) are bioaccumulating flame retardants causing developmental neurotoxicity (DNT) in humans and rodents. Their DNT effects are suspected to involve thyroid hormone (TH) signaling disruption. Here, we tested the hypothesis whether disturbance of neural progenitor c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dach, Katharina, Bendt, Farina, Huebenthal, Ulrike, Giersiefer, Susanne, Lein, Pamela J., Heuer, Heike, Fritsche, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357893/
https://ncbi.nlm.nih.gov/pubmed/28317842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44861
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