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Hemodynamic effects of phenoxybenzamine in anesthetized dogs

Our studies demonstrated that phenoxybenzamine, 10 mg/kg, administered intravenously to intact anesthetized dogs, produced an immediate and significant increase of heart rate and cardiac output. In heart-lung preparations, phenoxybenzamine had no effect or a negative cardiac inotropic effect, hence...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Fowler, Noble O., Holmes, John C., Gaffney, Thomas E., Privitera, Philip J., Grupp, Gunter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1970
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4394473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106423
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