Hemodynamic effects of phenoxybenzamine in anesthetized dogs

Our studies demonstrated that phenoxybenzamine, 10 mg/kg, administered intravenously to intact anesthetized dogs, produced an immediate and significant increase of heart rate and cardiac output. In heart-lung preparations, phenoxybenzamine had no effect or a negative cardiac inotropic effect, hence...

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Pubblicato in:	J Clin Invest
Autori principali:	Fowler, Noble O., Holmes, John C., Gaffney, Thomas E., Privitera, Philip J., Grupp, Gunter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1970
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4394473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106423
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