Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway

Cellular senescence is an important in vivo mechanism that prevents the propagation of damaged cells. However, the precise mechanisms regulating senescence are not well characterized. Here, we find that ITGB3 (integrin beta 3 or β3) is regulated by the Polycomb protein CBX7. β3 expression accelerate...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Rapisarda, Valentina, Borghesan, Michela, Miguela, Veronica, Encheva, Vesela, Snijders, Ambrosius P., Lujambio, Amaia, O’Loghlen, Ana
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2017
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357738/
https://ncbi.nlm.nih.gov/pubmed/28273461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.012
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares