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Vascular K(ATP) channels mitigate severe muscle O(2) delivery-utilization mismatch during contractions in chronic heart failure rats

The vascular ATP-sensitive K+ (K(ATP)) channel is a mediator of skeletal muscle microvascular oxygenation (PO(2)mv) during contractions in health. We tested the hypothesis that K(ATP) channel function is preserved in chronic heart failure (CHF) and therefore its inhibition would reduce PO(2)mv and e...

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書誌詳細
出版年:Respir Physiol Neurobiol
主要な著者: Holdsworth, Clark T., Ferguson, Scott K., Colburn, Trenton D., Fees, Alexander J., Craig, Jesse C., Hirai, Daniel M., Poole, David C., Musch, Timothy I.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357564/
https://ncbi.nlm.nih.gov/pubmed/28119150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2017.01.009
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