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Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

BACKGROUND: Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they...

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Pubblicato in:PeerJ
Autori principali: Wedd, Laura, Ashby, Regan, Foret, Sylvain, Maleszka, Ryszard
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357340/
https://ncbi.nlm.nih.gov/pubmed/28321369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3109
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