Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

BACKGROUND: Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they...

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Bibliographic Details
Published in:PeerJ
Main Authors: Wedd, Laura, Ashby, Regan, Foret, Sylvain, Maleszka, Ryszard
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2017
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357340/
https://ncbi.nlm.nih.gov/pubmed/28321369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3109
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