The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

The docking protein p140Cap negatively regulates tumour cell features. Its relevance on breast cancer patient survival, as well as its ability to counteract relevant cancer signalling pathways, are not fully understood. Here we report that in patients with ERBB2-amplified breast cancer, a p140Cap-po...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Grasso, Silvia, Chapelle, Jennifer, Salemme, Vincenzo, Aramu, Simona, Russo, Isabella, Vitale, Nicoletta, Verdun di Cantogno, Ludovica, Dallaglio, Katiuscia, Castellano, Isabella, Amici, Augusto, Centonze, Giorgia, Sharma, Nanaocha, Lunardi, Serena, Cabodi, Sara, Cavallo, Federica, Lamolinara, Alessia, Stramucci, Lorenzo, Moiso, Enrico, Provero, Paolo, Albini, Adriana, Sapino, Anna, Staaf, Johan, Di Fiore, Pier Paolo, Bertalot, Giovanni, Pece, Salvatore, Tosoni, Daniela, Confalonieri, Stefano, Iezzi, Manuela, Di Stefano, Paola, Turco, Emilia, Defilippi, Paola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357316/
https://ncbi.nlm.nih.gov/pubmed/28300085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14797
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