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X-ray Crystal Structure of the N-Terminal Region of Moloney Murine Leukemia Virus Integrase and its Implications for Viral DNA Recognition
The retroviral integrase (IN) carries out the integration of a dsDNA copy of the viral genome into the host DNA, an essential step for viral replication. All IN proteins have three general domains, the N-terminal domain (NTD), the catalytic core domain (CCD), and the C-terminal domain (CTD). The NTD...
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| Publicado no: | Proteins |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357174/ https://ncbi.nlm.nih.gov/pubmed/28066922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25245 |
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