Fasting-mimicking diet promotes Ngn3-driven β-cell regeneration to reverse diabetes

Stem cell-based therapies can potentially reverse organ dysfunction and diseases but the removal of impaired tissue and reactivation of the program leading to organ regeneration pose major challenges. In mice, a four-day fasting mimicking diet (FMD) induces a step-wise expression of Sox17 and Pdx-1,...

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Foilsithe in:Cell
Main Authors: Cheng, Chia-Wei, Villani, Valentina, Buono, Roberta, Wei, Min, Kumar, Sanjeeve, Yilmaz, Omer H., Cohen, Pinchas, Sneddon, Julie B., Perin, Laura, Longo, Valter D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357144/
https://ncbi.nlm.nih.gov/pubmed/28235195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.040
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