Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that in most cases induces irreversible necrosis of lung tissue as a result of excessive inflammatory reactions. The murine model of TB in resistant C57BL/6 mice infected with reference Mtb strains is widely...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Almeida, Fabrício M., Ventura, Thatiana L. B., Amaral, Eduardo P., Ribeiro, Simone C. M., Calixto, Sanderson D., Manhães, Marcelle R., Rezende, Andreza L., Souzal, Giliane S., de Carvalho, Igor S., Silva, Elisangela C., da Silva, Juliana Azevedo, Carvalho, Eulógio C. Q., Kritski, Afranio L., Lasunskaia, Elena B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357019/
https://ncbi.nlm.nih.gov/pubmed/28306733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173715
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