Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that in most cases induces irreversible necrosis of lung tissue as a result of excessive inflammatory reactions. The murine model of TB in resistant C57BL/6 mice infected with reference Mtb strains is widely...

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發表在:PLoS One
Main Authors: Almeida, Fabrício M., Ventura, Thatiana L. B., Amaral, Eduardo P., Ribeiro, Simone C. M., Calixto, Sanderson D., Manhães, Marcelle R., Rezende, Andreza L., Souzal, Giliane S., de Carvalho, Igor S., Silva, Elisangela C., da Silva, Juliana Azevedo, Carvalho, Eulógio C. Q., Kritski, Afranio L., Lasunskaia, Elena B.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357019/
https://ncbi.nlm.nih.gov/pubmed/28306733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173715
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