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Glucuronidation and UGT isozymes in bladder: new targets for the treatment of uroepithelial carcinomas?

Bladder cancer has been linked to numerous toxins which can be concentrated in the bladder after being absorbed into the blood and filtered by the kidneys. Excessive carcinogenic load to the bladder urothelium may result in the development of cancer. However, enzymes within the bladder can metaboliz...

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Publicat a:Oncotarget
Autors principals: Sundararaghavan, Vikram L., Sindhwani, Puneet, Hinds, Terry D.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356909/
https://ncbi.nlm.nih.gov/pubmed/27690298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12277
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