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Glucuronidation and UGT isozymes in bladder: new targets for the treatment of uroepithelial carcinomas?

Bladder cancer has been linked to numerous toxins which can be concentrated in the bladder after being absorbed into the blood and filtered by the kidneys. Excessive carcinogenic load to the bladder urothelium may result in the development of cancer. However, enzymes within the bladder can metaboliz...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sundararaghavan, Vikram L., Sindhwani, Puneet, Hinds, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356909/
https://ncbi.nlm.nih.gov/pubmed/27690298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12277
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