Robust detection of immune transcripts in FFPE samples using targeted RNA sequencing

Current criteria for identifying cancer patients suitable for immunotherapy with immune checkpoint blockers (ICBs) are subjective and prone to misinterpretation, as they mainly rely on the visual assessment of CD274 (best known as PD-L1) expression levels by immunohistochemistry (IHC). To address th...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Paluch, Benjamin E, Glenn, Sean T, Conroy, Jeffrey M, Papanicolau-Sengos, Antonios, Bshara, Wiam, Omilian, Angela R, Brese, Elizabeth, Nesline, Mary, Burgher, Blake, Andreas, Jonathan, Odunsi, Kunle, Eng, Kevin, He, Ji, Qin, Maochun, Gardner, Mark, Galluzzi, Lorenzo, Morrison, Carl D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356875/
https://ncbi.nlm.nih.gov/pubmed/27911273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13691
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