Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma

In this study, we aimed to identify novel drivers that would be epigenetically altered through aberrant methylation in early-stage lung adenocarcinoma (LADC), regardless of the presence or absence of tobacco smoking-induced epigenetic field defects. Through genome-wide screening for aberrantly methy...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kajiura, Koichiro, Masuda, Kiyoshi, Naruto, Takuya, Kohmoto, Tomohiro, Watabnabe, Miki, Tsuboi, Mitsuhiro, Takizawa, Hiromitsu, Kondo, Kazuya, Tangoku, Akira, Imoto, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356850/
https://ncbi.nlm.nih.gov/pubmed/27926516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13761
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