The tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signaling

We and others have shown that the Tissue Inhibitor of Metalloproteinases-1 (TIMP-1), a member of the inflammatory network exerting pleiotropic effects in the bone marrow (BM) microenvironment, regulates the survival and proliferation of different cell types, including normal hematopoietic progenitor...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Forte, Dorian, Salvestrini, Valentina, Corradi, Giulia, Rossi, Lara, Catani, Lucia, Lemoli, Roberto M., Cavo, Michele, Curti, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356797/
https://ncbi.nlm.nih.gov/pubmed/27903985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13664
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