PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

Nuclear receptors such as peroxisome proliferator-activated receptor α (PPARα) are potential therapeutic targets. In this study, we found that PPARα expression was lower in high grade gliomas and PPARα was an independent prognostic factor in GBM patients. PPARα agonism or overexpression inhibited gl...

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Vydáno v:Oncotarget
Hlavní autoři: Shi, Yan, Tao, Tao, Liu, Ning, Luan, WenKang, Qian, Jin, Li, Rui, Hu, Qi, Wei, Yan, Zhang, Junxia, You, Yongping
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356686/
https://ncbi.nlm.nih.gov/pubmed/27835866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13170
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