PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

Nuclear receptors such as peroxisome proliferator-activated receptor α (PPARα) are potential therapeutic targets. In this study, we found that PPARα expression was lower in high grade gliomas and PPARα was an independent prognostic factor in GBM patients. PPARα agonism or overexpression inhibited gl...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Shi, Yan, Tao, Tao, Liu, Ning, Luan, WenKang, Qian, Jin, Li, Rui, Hu, Qi, Wei, Yan, Zhang, Junxia, You, Yongping
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356686/
https://ncbi.nlm.nih.gov/pubmed/27835866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13170
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