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Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

Resistance to chemotherapy remains a challenge in the clinical management of diffuse B cell lymphomas despite aggressive chemotherapy such as CHOP and monoclonal CD20. Here we provide evidence that the apoptosome adaptor protein, Apaf-1, is mislocalized in primary cells derived from patients with di...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hirpara, Jayshree L., Loh, Thomas, Ng, Siok Bian, Chng, Wee Joo, Pervaiz, Shazib
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356638/
https://ncbi.nlm.nih.gov/pubmed/27863378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13336
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