NFI and Oct-1 bend the Ad5 origin in the same direction leading to optimal DNA replication

Two cellular transcription factors, nuclear factor I (NFI) and octamer binding protein (Oct-1), bind simultaneously to their recognition sequences in the Ad5 origin of replication thereby enhancing initiation. Using scanning force microscopy we have previously shown that NFI induces a 60° bend in th...

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Bibliographic Details
Main Authors: Mysiak, Monika E., Wyman, Claire, Holthuizen, P. Elly, van der Vliet, Peter C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC535662/
https://ncbi.nlm.nih.gov/pubmed/15576348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh944
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