Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.

Anti-Ku (p70/p80) autoantibodies in patients with scleroderma-polymyositis overlap syndrome recognize a 70-kDa/80-kDa protein heterodimer which binds to terminal regions of double-stranded DNA. In the present study, we isolated full-length cDNAs that encode the 80-kDa Ku subunit. Initial screening o...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mimori, T, Ohosone, Y, Hama, N, Suwa, A, Akizuki, M, Homma, M, Griffith, A J, Hardin, J A
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC53566/
https://ncbi.nlm.nih.gov/pubmed/2308937
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires