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The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription
The unrestrained proliferation of cancer cells requires a high level of ribosome biogenesis. The first stage of ribosome biogenesis is the transcription of the large ribosomal RNAs (rRNAs); the structural and functional components of the ribosome. Transcription of rRNA is carried out by RNA polymera...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356541/ https://ncbi.nlm.nih.gov/pubmed/27589844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11770 |
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