Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism

Human lactoferrin, a component of the innate immune system, kills a wide variety of microorganisms including the Gram positive bacteria Streptococcus pneumoniae. Pneumococcal surface protein A (PspA) efficiently inhibits this bactericidal action. The crystal structure of a complex of the lactoferrin...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Senkovich, Olga, Cook, William J., Mirza, Shaper, Hollingshead, Susan K., Protasevich, Irina I., Briles, David E., Chattopadhyay, Debasish
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356469/
https://ncbi.nlm.nih.gov/pubmed/17543335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.075
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