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Crystal Structure of Cryptosporidium parvum Pyruvate Kinase

Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically regulated by different effector molecules, mainly phosphosugars. In response to binding of effector molecules and substrates, significant st...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cook, William J., Senkovich, Olga, Aleem, Khadijah, Chattopadhyay, Debasish
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467265/
https://ncbi.nlm.nih.gov/pubmed/23056503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046875
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