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Crystal Structure of Cryptosporidium parvum Pyruvate Kinase

Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically regulated by different effector molecules, mainly phosphosugars. In response to binding of effector molecules and substrates, significant st...

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Hlavní autoři: Cook, William J., Senkovich, Olga, Aleem, Khadijah, Chattopadhyay, Debasish
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467265/
https://ncbi.nlm.nih.gov/pubmed/23056503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046875
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