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The Crystal Structure of Toxoplasma gondii Pyruvate Kinase 1
BACKGROUND: Pyruvate kinase (PK), which catalyzes the final step in glycolysis converting phosphoenolpyruvate to pyruvate, is a central metabolic regulator in most organisms. Consequently PK represents an attractive therapeutic target in cancer and human pathogens, like Apicomplexans. The phylum Apl...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939071/ https://ncbi.nlm.nih.gov/pubmed/20856875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012736 |
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