The Crystal Structure of Toxoplasma gondii Pyruvate Kinase 1

BACKGROUND: Pyruvate kinase (PK), which catalyzes the final step in glycolysis converting phosphoenolpyruvate to pyruvate, is a central metabolic regulator in most organisms. Consequently PK represents an attractive therapeutic target in cancer and human pathogens, like Apicomplexans. The phylum Apl...

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Dettagli Bibliografici
Autori principali: Bakszt, Rebecca, Wernimont, Amy, Allali-Hassani, Abdellah, Mok, Man Wai, Hills, Tanya, Hui, Raymond, Pizarro, Juan C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939071/
https://ncbi.nlm.nih.gov/pubmed/20856875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012736
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