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Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii

Serine/threonine kinases secreted from rhoptry organelles constitute important virulence factors of Toxoplasma gondii. Rhoptry kinases are highly divergent and their structures and regulatory mechanism are hitherto unknown. Here, we report the X-ray crystal structures of two related pseudokinases na...

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Detalhes bibliográficos
Main Authors: Qiu, Wei, Wernimont, Amy, Tang, Keliang, Taylor, Sonya, Lunin, Vladimir, Schapira, Matthieu, Fentress, Sarah, Hui, Raymond, Sibley, L David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670854/
https://ncbi.nlm.nih.gov/pubmed/19197235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.24
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