Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma

BACKGROUND: The O (6)-methylguanine methyltransferase (MGMT) gene is frequently unmethylated in patients with glioblastoma (GBM), rendering them non-responsive to the standard treatment regime of surgery followed by concurrent radiotherapy (RT) and temozolomide. Here, we investigate the efficacy of...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Transl Med
Hlavní autoři: Jue, Toni Rose, Nozue, Kyoko, Lester, Ashleigh J., Joshi, Swapna, Schroder, Lisette B. W., Whittaker, Shane P., Nixdorf, Sheri, Rapkins, Robert W., Khasraw, Mustafa, McDonald, Kerrie L.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356284/
https://ncbi.nlm.nih.gov/pubmed/28314386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1164-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky