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Signature of an aggregation-prone conformation of tau

The self-assembly of the microtubule associated tau protein into fibrillar cell inclusions is linked to a number of devastating neurodegenerative disorders collectively known as tauopathies. The mechanism by which tau self-assembles into pathological entities is a matter of much debate, largely due...

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Foilsithe in:Sci Rep
Main Authors: Eschmann, Neil A., Georgieva, Elka R., Ganguly, Pritam, Borbat, Peter P., Rappaport, Maxime D., Akdogan, Yasar, Freed, Jack H., Shea, Joan-Emma, Han, Songi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356194/
https://ncbi.nlm.nih.gov/pubmed/28303942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44739
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