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Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature

BACKGROUND: Tumours are diverse ecosystems with persistent heterogeneity in various cancer hallmarks like self-sufficiency of growth factor production for angiogenesis and reprogramming of energy metabolism for aerobic glycolysis. This heterogeneity has consequences for diagnosis, treatment and dise...

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Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Kaznatcheev, Artem, Vander Velde, Robert, Scott, Jacob G, Basanta, David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355932/
https://ncbi.nlm.nih.gov/pubmed/28183139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.5
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