Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-γ

Th17 cells and the cytokine they produce, interleukin (IL)-17, play an important role in tumor progression in humans and in mice. IL-6 and IL-23 are critical cytokines for the differentiation and propagation of Th17 cells, respectively. Bacterial lipopolysaccharides (LPS) are known to stimulate immu...

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Bibliographic Details
Published in:Oncol Rep
Main Authors: Okuyama, Hiromi, Tominaga, Akira, Fukuoka, Satoshi, Taguchi, Takahiro, Kusumoto, Yutaka, Ono, Shiro
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355664/
https://ncbi.nlm.nih.gov/pubmed/28075473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5346
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