Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential

Epstein-Barr virus (EBV) infection is associated with B cell lymphomas in humans. The ability of EBV to convert human B cells into long-lived lymphoblastoid cell lines (LCLs) in vitro requires the collaborative effects of EBNA2 (which hijacks Notch signaling), latent membrane protein 1 (LMP1) (which...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Ma, Shi-Dong, Tsai, Ming-Han, Romero-Masters, James C., Ranheim, Erik A., Huebner, Shane M., Bristol, Jillian A., Delecluse, Henri-Jacques, Kenney, Shannon C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Transformation and Oncogenesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355617/
https://ncbi.nlm.nih.gov/pubmed/28077657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01928-16
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