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Rotation Mechanism of Molecular Motor V(1)-ATPase Studied by Multiscale Molecular Dynamics Simulation

Enterococcus hirae V(1)-ATPase is a molecular motor composed of the A(3)B(3) hexamer ring and the central stalk. In association with ATP hydrolysis, three catalytic AB pairs in the A(3)B(3) ring undergo conformational changes, which lead to a 120° rotation of the central stalk. To understand how the...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Isaka, Yuta, Ekimoto, Toru, Kokabu, Yuichi, Yamato, Ichiro, Murata, Takeshi, Ikeguchi, Mitsunori
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355535/
https://ncbi.nlm.nih.gov/pubmed/28297650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.01.029
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