Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy

The present study reports the behavioral, electrophysiological, and neuropathological effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the intrahippocampal pilocarpine-induced status epilepticus (SE) rat model. CBD was administered before pilocarpine-induced...

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Vydáno v:Front Pharmacol
Hlavní autoři: Do Val-da Silva, Raquel A., Peixoto-Santos, Jose E., Kandratavicius, Ludmyla, De Ross, Jana B., Esteves, Ingrid, De Martinis, Bruno S., Alves, Marcela N. R., Scandiuzzi, Renata C., Hallak, Jaime E. C., Zuardi, Antonio W., Crippa, Jose A., Leite, Joao P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355474/
https://ncbi.nlm.nih.gov/pubmed/28367124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00131
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