Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy

The present study reports the behavioral, electrophysiological, and neuropathological effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the intrahippocampal pilocarpine-induced status epilepticus (SE) rat model. CBD was administered before pilocarpine-induced...

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Udgivet i:Front Pharmacol
Main Authors: Do Val-da Silva, Raquel A., Peixoto-Santos, Jose E., Kandratavicius, Ludmyla, De Ross, Jana B., Esteves, Ingrid, De Martinis, Bruno S., Alves, Marcela N. R., Scandiuzzi, Renata C., Hallak, Jaime E. C., Zuardi, Antonio W., Crippa, Jose A., Leite, Joao P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355474/
https://ncbi.nlm.nih.gov/pubmed/28367124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00131
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