Protective Effects of Cannabidiol against Seizures and Neuronal Death in a Rat Model of Mesial Temporal Lobe Epilepsy

The present study reports the behavioral, electrophysiological, and neuropathological effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the intrahippocampal pilocarpine-induced status epilepticus (SE) rat model. CBD was administered before pilocarpine-induced...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Do Val-da Silva, Raquel A., Peixoto-Santos, Jose E., Kandratavicius, Ludmyla, De Ross, Jana B., Esteves, Ingrid, De Martinis, Bruno S., Alves, Marcela N. R., Scandiuzzi, Renata C., Hallak, Jaime E. C., Zuardi, Antonio W., Crippa, Jose A., Leite, Joao P.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355474/
https://ncbi.nlm.nih.gov/pubmed/28367124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00131
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