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LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer

Lysyl oxidase (LOX) family genes catalyze collagen cross-link formation. To determine the effects of lysyl oxidase-like 4 (LOXL4) expression on breast tumor formation and metastasis, we evaluated primary tumor growth and lung metastasis in mice injected with LOXL4-knockdown MDA-MB-231 triple-negativ...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Choi, Sul Ki, Kim, Hoe Suk, Jin, Tiefeng, Moon, Woo Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355319/
https://ncbi.nlm.nih.gov/pubmed/28060764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14450
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