LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer

Colorectal cancer (CRC) is a serious public health problem and non-invasive biomarkers improving diagnosis or therapy are strongly required. Circulating cell-free DNA (cfDNA) has been a promising target for this purpose. In this study, we evaluated the potential of long interspersed nuclear element-...

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Pubblicato in:Oncotarget
Autori principali: Nagai, Yuzo, Sunami, Eiji, Yamamoto, Yoko, Hata, Keisuke, Okada, Satoshi, Murono, Koji, Yasuda, Koji, Otani, Kensuke, Nishikawa, Takeshi, Tanaka, Toshiaki, Kiyomatsu, Tomomichi, Kawai, Kazushige, Nozawa, Hiroaki, Ishihara, Soichiro, Hoon, Dave S.B, Watanabe, Toshiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355314/
https://ncbi.nlm.nih.gov/pubmed/28060757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14439
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