Increased Copy Number Variation of mtDNA in an Array-based Digital PCR Assay Predicts Ulcerative Colitis-associated Colorectal Cancer

Aim: Mitochondrial dysfunction plays a central role in carcinogenesis in numerous cancer-related diseases. We examined the copy number variation of mitochondrial DNA (mtDNA) and the expression of energy-producing genes in relation to ulcerative colitis (UC)-associated carcinogenesis. Materials and M...

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Publicado no:In Vivo
Main Authors: TANAKA, TOSHIAKI, KOBUNAI, TAKASHI, YAMAMOTO, YOKO, MURONO, KOJI, OTANI, KENSUKE, YASUDA, KOJI, NISHIKAWA, TAKESHI, KIYOMATSU, TOMOMICHI, KAWAI, KAZUSHIGE, HATA, KEISUKE, NOZAWA, HIROAKI, ISHIHARA, SOICHIRO, WATANABE, TOSHIAKI
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566928/
https://ncbi.nlm.nih.gov/pubmed/28652445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11119
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