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Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer

PURPOSE: Dexamethasone (Dex), a glucocorticoid (GC), is used as a pretreatment drug in cancer patients undergoing chemotherapy. Dex functions by binding to the glucocorticoid receptor (GR) to prevent allergic reactions and severe chemotherapeutic side effects such as nausea and vomiting. However, th...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Li, Zhen, Dong, Jian, Zou, Tianning, Du, Chengzhi, Li, Siyuan, Chen, Ceshi, Liu, Rong, Wang, Kunhua
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355285/
https://ncbi.nlm.nih.gov/pubmed/28030791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14135
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