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Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer

PURPOSE: Dexamethasone (Dex), a glucocorticoid (GC), is used as a pretreatment drug in cancer patients undergoing chemotherapy. Dex functions by binding to the glucocorticoid receptor (GR) to prevent allergic reactions and severe chemotherapeutic side effects such as nausea and vomiting. However, th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Zhen, Dong, Jian, Zou, Tianning, Du, Chengzhi, Li, Siyuan, Chen, Ceshi, Liu, Rong, Wang, Kunhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355285/
https://ncbi.nlm.nih.gov/pubmed/28030791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14135
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