Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation

The triple-negative breast cancer subtype is highly aggressive and has no defined therapeutic target. Fyn-related kinase (FRK) is a non-receptor tyrosine kinase, reported to be downregulated in breast cancer and gliomas, where it is suggested to have tumor suppressor activity. We examined the expres...

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Udgivet i:Oncotarget
Main Authors: Bagu, Edward T., Miah, Sayem, Dai, Chenlu, Spriggs, Travis, Ogunbolude, Yetunde, Beaton, Erika, Sanders, Michelle, Goel, Raghuveera K., Bonham, Keith, Lukong, Kiven E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355277/
https://ncbi.nlm.nih.gov/pubmed/28077797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14546
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