Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

Spinal muscular atrophy (SMA) is a lethal autosomal recessive neurological disease characterized by selective degeneration of motor neurons in the spinal cord. In recent years, the development of cellular reprogramming technology has provided an alternative and effective method for obtaining patient...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Qi-Jie, Li, Jin-Jing, Lin, Xiang, Lu, Ying-Qian, Guo, Xin-Xin, Dong, En-Lin, Zhao, Miao, He, Jin, Wang, Ning, Chen, Wan-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355236/
https://ncbi.nlm.nih.gov/pubmed/28099929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14641
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