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Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy
Establishing human cell models of spinal muscular atrophy (SMA) to mimic motor neuron-specific phenotypes holds the key to understanding the pathogenesis of this devastating disease. Here, we developed a closely representative cell model of SMA by knocking down the disease-determining gene, survival...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587706/ https://ncbi.nlm.nih.gov/pubmed/23208423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.166 |
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