Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

PURPOSE: In the context of prostate cancer (PCa) imaging, the aim of this study was to optimize (in vitro) the specificity and assess preclinically (in vivo) the tumor targeting properties of the (123)I-scFvD2B antibody specific for prostate-specific membrane antigen (PSMA). EXPERIMENTAL DESIGN: The...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Frigerio, Barbara, Franssen, Gerben, Luison, Elena, Satta, Alessandro, Seregni, Ettore, Colombatti, Marco, Fracasso, Giulio, Valdagni, Riccardo, Mezzanzanica, Delia, Boerman, Otto, Canevari, Silvana, Figini, Mariangela
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355234/
https://ncbi.nlm.nih.gov/pubmed/28051996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14229
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