MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN

Approximately 15–40% of the general adult population suffers from non-alcoholic fatty liver disease (NAFLD) worldwide. However, no drug is currently licensed for its treatment. In this study, we observed a significant reduction of miR-30c-5p in the liver of leptin receptor-deficient (db/db) mice. Re...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Fan, Jiahui, Li, Huaping, Nie, Xiang, Yin, Zhongwei, Zhao, Yanru, Chen, Chen, Wang, Dao Wen
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355111/
https://ncbi.nlm.nih.gov/pubmed/28088781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14561
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